4 Comments
Jan 24, 2023Liked by Todd Hargrove

I think a variable in the study that can’t be controlled is what type of person reaches for the NSAID vs the person that says, I’ll rub some dirt on it and move on.

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Surgery is a controlled "injury" to various tissues in order to fix underlying issues, and we regularly use cryotherapy for TKRs for example. I know after both of my arthroscopies the codeine/percs I was given didn't work for pain control at all, but ice did. I'm curious how that fits in to this picture.

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Glad to have found this! Great article! I just wrote about it (albeit in a short and sweet version) on my Newsletter “Youth Sports Reimagined”

gradyatc.substack.com

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I wonder what anti-flammatory effects from Cannabidiol (CBD) based therapies - which are growing in popularity due to ease of access for study in many regions - might also contribute to this. Could we be further diminishing the ability of the body to heal itself by inappropriately suppressing inflammation?

CBD has also been shown to suppress neutrophil activity, in chronic use with epilepsy patients:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001508/

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